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DHX8 Antibody

  • 货号：
    CSB-PA002114
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HepG2 cells using DDX8 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q14562
  • 基因名：
    DHX8
  • 别名：
    ATP dependent RNA helicase DHX8 antibody; ATP-dependent RNA helicase dhx8 antibody; DDX 8 antibody; DDX8 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase) antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 antibody; DEAD/H box 8 antibody; DEAD/H box polypeptide 8 antibody; DEAH (Asp Glu Ala His) box polypeptide 8 antibody; DEAH box polypeptide 8 antibody; DEAH box protein 8 antibody; DHX 8 antibody; dhx8 antibody; DHX8_HUMAN antibody; HRH 1 antibody; HRH1 antibody; PRP 22 antibody; PRP22 antibody; PRP22; S. cerevisiae; homolog of antibody; PRPF 22 antibody; PRPF22 antibody; RNA helicase HRH 1 antibody; RNA helicase HRH1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DDX8.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
  • 基因功能参考文献：
    1. cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
    2. structural and functional analysis of C-terminal domain of the spliceosomal helicase Prp22 PMID: 23096351
    3. Preliminary X-ray diffraction analysis of the crystals of the C-terminal domain of the human DExD/H-box protein hPrp22 at 2.1 A resolution, is reported. PMID: 19724143
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    DEAD box helicase family, DEAH subfamily, DDX8/PRP22 sub-subfamily
  • 组织特异性：
    Expressed in skin, cervix and nerve. Also expressed in the brain.
  • 数据库链接：

    HGNC: 2749

    OMIM: 600396

    KEGG: hsa:1659

    STRING: 9606.ENSP00000262415

    UniGene: Hs.463105